|
KMID : 0191120070220040682
|
|
Journal of Korean Medical Science
2007 Volume.22 No. 4 p.682 ~ p.686
|
|
|
Analysis of Methicillin Resistance among Staphylococcus aureus Blood Isolates in an Emergency Department
|
|
Heo Sang-Taek
Kwon Ki-Tae
Song Jae-Hoon
Lee Nam-Yong
Oh Won-Sup
Ko Kwan-Soo
Ryu Seong-Yeol
Peck Kyong-Ran
|
|
|
Abstract
|
|
|
|
The increasing prevalence of methicillin-resistant Staphylococcus aureus (MRSA) has become of great concern in both hospital and community settings. To evaluate the prevalence and risk factors for methicillin resistance among Staphylococcus aureus, blood isolates in our Emergency Department (ED) were collected. All patients with S. aureus bacteremia (SAB) who presented to the ED from January 2000 to August 2005 were included, and a retrospective study was performed. A total of 231 patients with SAB were enrolled (median age, 59 yr; M:F, 125:106). Among these patients, methicillin-resistant strains accounted for 27.3% (63 patients). Catheter-related infection was the most frequent primary site of SAB (39.0%), followed by skin and soft tissue infection (16.5%). In multivariate analysis, recent surgery (OR, 3.41; 95% CI, 1.48-7.85), recent hospitalization (2.17; 1.06-4.62), and older age (> or =61 yr) (2.39; 1.25-4.57) were independently associated with the acquisition of methicillin-resistant strains. When antimicrobial therapy is considered for the treatment of a patient with suspected SAB, clinicians should consider obtaining cultures and modifying empirical therapy to provide MRSA coverage for patients with risk factors: older age, recent hospitalization, and recent surgery
|
|
|
KEYWORD
|
|
|
Staphylococcus aureus, Community-acquired Infections, Methicillin Resistance, Risk Factors
|
|
|
FullTexts / Linksout information
|
|
 
|
|
|
Listed journal information
|
|
    
|
|